Clarithromycin containing triple therapy Helicobacter pylori eradication compared with levofloxacin containing triple therapy

INTERVENTION: Control group: Panto Prazol 40 mg twice daily , amoxicillin 1g , clarithromycin 500 mg twice daily for 10 days Groups intervention: pantoprazole 40 mg twice daily, amoxicillin 1 g, levofloxacin 500 mg once daily for 10 days Intervention 1: Control group: Panto Prazol 40 mg twice daily , amoxicillin 1g , clarithromycin 500 mg twice daily for 10 days. Intervention 2: Groups intervention: pantoprazole 40 mg twice daily, amoxicillin 1 g, levofloxacin 500 mg once daily for 10 days. Treatment ‐ Drugs CONDITION: Eradication of Helicobacter pylori. ; Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters PRIMARY OUTCOME: Eradication of Helicobacter pylor. Timepoint: 10 days after treatment,4 Weeks after treatment ppI,Four weeks after discontinuation of medication for respiratory test. Method of measurement: Through the breath test 14 C‐ UBT. SECONDARY OUTCOME: Bitter mouth. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Changes in taste. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Constipation Decreased appetite. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Diarrhea‐vomiting. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Headache?Dizziness?Confusion. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Nausea , abdominal pain. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Side effects reported by patients include hypersensitivity reactions. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. Skin complications. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview. INCLUSION CRITERIA: INCLUSION CRITERIA: All patients underwent endoscopy with duodenal ulcer or gastric or duodenal or stomach inflammation and Erosion referred to the clinic / office professor interviewed Sari hospital reported that Helicobacter pylori positive and study are older than 18 years Exclusion criteria: Pregnancy and breastfeeding; H. pylori eradication has already been received; During the last two weeks patients with PPI or H2 RA (histamine 2 receptor antagonist), or within the last 4 weeks have received antibiotics or bismuth; Concomitant use of anticoagulants; corticosteroids or ketoconazole; Patients with a history of stomach surgery; Patients with advanced disease confirmed and severe cardiac; pulmonary;Endocrine; chronic renal failure; chronic liver disease and cancer; alcohol consumption; With a history of peptic ulcer bleeding ulcer complications