comparison between Intralesional injection of 2% zinc sulfate and intralesional glucantime in treatment of cutaneous leishmaniasis.

INTERVENTION: intraleisional injection of zinc sulfate 2% vial once every week until 10 weeks or until complete healing if happened earliear plus crotherapy at ‐196 degree celsius (liqiud nitrogen) once every other week until 10 weeks or until complete healing if happened earliear; it is performed as contact cryotherapy for 5‐10 sec to the infected site CONDITION: leishmaniasis PRIMARY OUTCOME: size of induration is measured with a transparent paper by an independed observer who was blind to the treat options SECONDARY OUTCOME: smear for leishmaniasis INCLUSION CRITERIA: the patients with urban cutaneous leishmaniasis with the onset of lower than 3 months