Gastrointestinal bleeding complicating antiplatelet treatment after percutaneous coronary intervention(PCI)

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2009
INTERVENTION: endoscopic findings is normal and no symptom case: they randomly divided into three treatment arms in each of the groups. Each group was randomly assigned to receive 10 mg omeprazole once a day after breakfast, 100 mg rebamipide 3 times per day after each meal, or no receiving drug during 6 months. patients have endoscopic findings and/or symptom : they randomly divided into two treatment arms in each of the groups. Each group was randomly assigned to receive 10 mg omeprazole once a day after breakfast, 100 mg rebamipide 3 times per day after each meal 6 months. when patients have peptic uler, they received H. pylori eradication therapy. afer that, they receive 10 mg omeprazole once a day after breakfast. CONDITION: patients for indicated antiplatelet treatment after percutaneous coronary intervention(PCI) PRIMARY OUTCOME: The current study attempted to compare the efficacy of rabeprazole with omeprazole in patients indicated for antiplatelet treatment after PCI SECONDARY OUTCOME: upper gastrointestinal bleeding.; Gastrointestinal symptom(Gastrointesitinal Symptom Rating Scale). INCLUSION CRITERIA: patients indicated for antiplatelet treatment(aspirin and clopidogrel) after percutaneous coronary intervention(PCI)
Epistemonikos ID: c07e451877687234be9f28fd4de16190fd8cdee9
First added on: Aug 22, 2024