Comparing the efficacy of transforaminal epidural steroid combined hyaluronic acid versus steroid combined hyaluronidase injection in improvement of function and pain related to lumbosacral disk herniation, A Randomized Clinical Trial

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2026
INTERVENTION: Intervention group: steroid‐hyaluronic‐acid, control group:steroid‐hyaluronidase. CONDITION: lumbar disc herniation and lumbar spinal stenosis. PRIMARY OUTCOME: . Timepoint: . Method of measurement: . Pain and function. Timepoint: Before the intervention, 1 month, 3 months and 6 months after the intervention. Method of measurement: Pain assessment with visual analog scale, function assessment with Roland‐Morris questionnaire and Oswestry Disability Index. INCLUSION CRITERIA: patients aged 20 to 65 years with a BMI <33 with radicular back pain of lumbar disc origin that has not responded to conservative treatments within 6 weeks of treatment. Positive MRI findings of intervertebral disc herniation and canal stenosis or intervertebral foramen stenosis and positive clinical tests in favor of intervertebral disc involvement and lumbar root involvement in EMG/NCS
Epistemonikos ID: bf302e3e05181565d0ebb92fab488fe7082ef45d
First added on: Aug 08, 2026