Serial endoscopic evaluation of aspirin-induced gastroduodenal injury: pevention of peptic ulcer with proton pump inhibitor in patients taking low-dose aspirin

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2010
INTERVENTION: Raveprazole (10 mg) will be given for 3 months in patinets who undergo PCI and take aspirin, after confirming the absence of endoscopic upper GI ulcer. Placebo will be given for 3 months in patinets who undergo PCI and take aspirin, after confirming the absence of endoscopic upper GI ulcer. CONDITION: Coronay artery disase Gastroduodenal ulcer PRIMARY OUTCOME: Gastroduodenal Ulcer or bleeding, Upper Gastrointestinal symptom and decrease in hemoglobin level 3 month after percutaneous coronary intervention SECONDARY OUTCOME: Severity of gastroduodenal mucosal injury evaluated with LANZA score INCLUSION CRITERIA: Patients with Coronary artery disease Patients who underwent Percutaneous coronary intervention using coronary stent Patinets who were treated with anti‐platelets including aspirin
Epistemonikos ID: bee0c52fab76d0c11ce788ab7d9b9cd0ac403a06
First added on: Aug 22, 2024