Antidepressant effect of 5-methoxypsoralen: a preliminary report.

Category Primary study
JournalPsychopharmacology
Year 1988
5-Methoxypsoralen (5 MOP) administered daily (40 mg at 9 p.m.) was compared with placebo in the treatment of severe depression. The clinical response was evaluated using the Hamilton Depression Rating Scale after 1 week of treatment. Our preliminary data indicate that patients receiving 5 MOP improved significantly after 1 week, whereas patients treated with placebo did not. The stimulating effect of 5 MOP on the melatonin secretion may be involved in this clinical effect.
Epistemonikos ID: becea051667a9f0048a9634644090ba861e423a1
First added on: Sep 10, 2023