A control study of antipsychotic combined with MECT in treatment-resistant schizophrenia

OBJECTIVE: To evaluate the clinical efficacy of antipsychotics combined with non-refractory schizophrenia modified electric convulsive therapy. METHODS: 90 patients with refractory schizophrenia were randomly divided into two groups, study group of 50 patients in the control group of 40 patients, two groups conventional antipsychotics were applied, the joint Study group modified electroconvulsive shock treatment on this basis, 12 weeks. positive and negative Syndrome scale to assess the clinical efficacy. the results of each study group therapy session the positive and negative symptom scale scores significantly lower than the control group (P <0.05); the treatment of 12 weeks, the study group was 52.0% efficiency, the total efficiency of 88.0%, the control group were 27.5%, 72.5%, the study group was efficient, total effective rate was significantly higher than that the control group (P <0.05). CONCLUSION: antipsychotics joint MECT treatment of refractory schizophrenia significant, rapid onset was significantly better than with antipsychotic drugs.