A randomized control trial for preventing decline of cognitive functions in the community living elderly with mild cognitive impairment

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2010
INTERVENTION: Intervention group: Supervised aerobic exercise for 1 year Control group: Lecture about disease and health (3 times per year) CONDITION: mild cognitive impairment PRIMARY OUTCOME: Cognitive function: ADAS; Brain volumetry: MRI; Brain function: FDG PET and fNIRS SECONDARY OUTCOME: Cognitive functions: Mini‐mental state examination, Clinical dementia rating, Wechsler memory scale‐R, Digit span, Stroop test, SDMT, Word fluency, Trail making test, Geriatric depression scale, Clock drawing, VBTA, Ray‐Osterrieth complex figure test, Raven's Colored Progressive Matrices, Key search test, A part of standard language test of aphasia; Physical functions: muscle strength, gait performance; Activity: Tokyo Metropolitan Institute of Gerontology Index, Life‐space assessment INCLUSION CRITERIA: 1) Living in Obu city 2) CDR 0.5 3) give a written informed consent to the participation in the present study
Epistemonikos ID: bdbf5d72e094e9eb2c16ee67f30f34b58381336a
First added on: Aug 22, 2024