Cost-effectiveness of TPMT Pharmacogenetics

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2007
The purpose of this study is to determine whether thiopurine S-methyltransferase (TPMT) genotyping prior to thiopurine use is cost-effective in patients with inflammatory bowel disease (IBD) in need of immune suppression. The study is designed to test the hypothesis that optimization of initial thiopurine dose based on pre-treatment TPMT genotyping will maximize treatment efficacy and minimize adverse drug reactions (ADRs) resulting in reduced costs.
Epistemonikos ID: bdb1a8f1846ed26c5b15a1b939fe5d7da6cec355
First added on: Mar 23, 2022