Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2012
This phase 1 trial studies the side effects and the best dose of donor CD8+ memory T-cells in treating patients with hematolymphoid malignancies. Giving low dose of chemotherapy before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may also stop the patient\'s immune system from rejecting the donor\'s stem cells. The donated stem cells may replace the patient\'s immune cells and help destroy any remaining cancer cells (graft-versus-cancer effects). Giving an infusion of the donor\'s T cells (donor lymphocyte infusion) after the transplant may help increase this effect
Epistemonikos ID: bb951a7c077c4fe555e3a8d1251029062c3a93cb
First added on: May 10, 2024