To observe the effect of acupuncture on regulating gastrointestinal tract on intestinal flora structure in adolescents with depression

INTERVENTION: acupuncture group:acupuncture;sham acupuncture group:sham acupuncture; CONDITION: Depression PRIMARY OUTCOME: SDS;BDI‐II;HAMD; SECONDARY OUTCOME: NE;ALFF\ReHo\FC;GABA;BDNF;intestinal flora structure;CORT;SCFAs;5‐HT;DA; INCLUSION CRITERIA: 1) Diagnostic criteria The diagnostic criteria of western medicine refer to the criteria of depression in the Chinese Classification and Diagnostic Criteria of Mental Disorders Third Edition (CCMD‐3). The diagnostic criteria of TCM refer to the criteria of depressive syndrome in the Diagnostic Efficacy Criteria of TCM Diseases and Syndromes. 2) Inclusion criteria Meet the above diagnostic criteria; Aged 12‐18 years; Clear consciousness, stable vital signs, with certain expressive power; The total score of Hamilton Depression Scale (HAMD) was more than 20 points. Approved by the ethics committee of our hospital and agreed to sign the informed consent form for the trial.