Does mouthrinsing and gargling with povidone iodine and hydrogen peroxide reduce the number of SARS-CoV-2 viruses in patients with no and mild symptoms?

INTERVENTION: Research subjects were given mouthrinsing and gargling protocol education through video conference and given mouthrinse that had been repackaged. The 1% povidone iodine group rinsed with BETADINE® Mouthwash and Gargle solution. The 3% hydrogen peroxide group rinsed with a solution from OneMed™. The group of 0.5% povidone iodine and 1.5% hydrogen peroxide rinsed with a diluted solution of 1% iodine povidone BETADINE® Mouthwash and Gargle and 3% hydrogen peroxide OneMed™ added with sterile distilled water with the formula Volume1 x Concentration1=Volume2 x Concentration2. There were two intervention groups and one control group: ‐ Intervention 1: 1% povidone iodine ‐ Intervention 2: 0.5% povidone iodine ‐ Intervention 3: 3% hydrogen peroxide ‐ Intervention 4: 1.5% hydrogen peroxide ‐ Control: mineral water Research subjects performed mouthrinsing for 30 seconds in the oral cavity and gargling and 30 seconds in the back of the throat with 15 mL of mouthrinse 3 times a day for 5 days. The mouthrinsing and gargling activity was carried out in the self‐isolation room of each research subject by using video conference. CONDITION: COVID‐19 (SARS‐CoV‐2 infection) ; Infections and Infestations PRIMARY OUTCOME: Viral load measured using CT value of the RT‐PCR examination on day 1, day 3 and day 5 after the mouthrinsing and gargling intervention SECONDARY OUTCOME: There are no secondary outcome measures INCLUSION CRITERIA: 1. Patients of Persahabatan Central General Hospital, (COVID‐19 national referral centre) 2. Patients infected with SARS‐CoV‐2 and identified through RT‐PCR with positive results at Persahabatan Central General Hospital during 1st July – 30th September 2021 with CT values = 30 3. Asymptomatic patients or with mild symptoms 4. Patients being diagnosed with COVID‐19 for less than three days 5. Aged 19 ‐ 60 years old