A study of the effectiveness of the Air Quality Health Index (AQHI) in reducing harmful effects of air pollution on the heart and lungs in adults 55 and over

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2015
INTERVENTION: 1. The intervention group will be asked to exercise indoors rather than outdoors and avoid other outdoor activity prior to physiological testing when the maximum AQHI is forecast to be 5 or higher (on the remaining days they will exercise outdoors). The intervention group will receive instructions for a simple indoor exercise routine that can be completed on designated days. 2. The control group will exercise outdoors daily CONDITION: Cardiac and respiratory health ; Signs and Symptoms ; Symptoms and signs involving the circulatory and respiratory systems PRIMARY OUTCOME: Weekly measures before and after 30 minutes of mild activity:; 1. Heart rate variability (Holter monitoring); 2. Endothelial function (Reactive Hyperemia Index ‐ Peripheral artery tone); 3. Oxygen saturation (finger oximeter); 4. Blood pressure (automated sphygmomanometer); 5. Fraction of exhaled Nitric Oxide (exhaled NO sensor); 6. Spirometric measures (spirometer); 7. Urinary oxidative stress markers (vascular endothelial growth factor (VEGF), 8‐isoprostane, malondialdehyde (MDA), 8‐hydroxydeoxyguanosine (8‐OHdG)) SECONDARY OUTCOME: Respiratory symptoms. INCLUSION CRITERIA: 1. Participants must be 55 years of age or older 2. Non‐smokers 3. Not exposed to environmental tobacco smoke at home 4. No seasonal allergies
Epistemonikos ID: b9a91015b3177ae609646f4378d0b0826cb16ae6
First added on: Aug 23, 2024