Study to Evaluate Benefit of ProbioSatys™ on Weight Reduction in Overweight Subjects

ProbioSatys™ is a probiotic nutritional solution containing a commensal Enterobacteriaceae food grade strain, Hafnia alvei 4597. The microbiome is known to play a crucial role in body weight management and metabolic disease. ProbioSatys™ mechanism of action relies on bacterial metabolites that send local and central signals via the gut‐brain axis by molecularly mimicking satiety hormones involved in appetite regulation. Numerous ProbioSatys™pre‐clinical studies indicate that consumption of the strain leads to body weight loss based on food intake reduction, but also improvement of body composition (increase of lean mass/fat mass ratio), and improvement of glucose metabolism (oral glucose tolerance test, and fasted glycemia). The present study aims to evaluate the effects of ProbioSatys™ on body weight and related parameters in overweight subjects during a 12‐week consumption period. In addition, tolerability and safety of ProbioSatys™ will be assessed.