Clinical Efficacy of Radiofrequency Treatment of the C2 Nerve for Migraine

INTERVENTION: Control Group:Standard pharmacological therapy with oral flunarizine;PRF Group:Percutaneous pulsed radiofrequency (PRF) treatment targeting the C2 nerve root;RFT Group:Percutaneous conventional radiofrequency thermocoagulation (RFT) of the C2 nerve root; CONDITION: frontotemporal pain associated with migraine PRIMARY OUTCOME: Change from baseline in headache attack frequency at 6 months post‐intervention; SECONDARY OUTCOME: Migraine Disability Assessment Scale;Monthly frequency of acute medication (triptan) use;Pituitary Adenylate Cyclase Activating Polypeptide, PACAP;Pain Visual Analogue Scale;Headache Impact Test‐6;Calcitonin Gene‐Related Peptide, CGRP ;Duration of headache attacks;Migraine‐Specific Quality of Life Questionnaire version 2.1; INCLUSION CRITERIA: 1. Diagnosis of migraine according to the International Classification of Headache Disorders, 3rd edition (ICHD‐3, 2018) criteria; 2. Age >=18 years, either sex; 3. Pain intensity >=4 on a 0‐10 Visual Analog Scale (VAS); 4. ASA physical status I or II (American Society of Anesthesiologists classification); 5. Brain MRI demonstrating no secondary causes for headache; 6. Provision of signed informed consent prior to study participation.