Preemptive use of drugs improves Endodontic Treatment of symptomatic teeth

Authors
Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2023
INTERVENTION: D27.505.696.663.850.014.040.500 E06.397 This is a three‐arm, double‐blind, randomized controlled clinical trial. Control group: 28 patients will receive endodontic treatment and will receive the administration (orally) of a pill of a placebo medicine in a single dose 60 minutes before the treatment. Experimental group 1: 28 patients will receive endodontic treatment and will receive the administration (orally) of a 4 mg dexamethasone tablet in a single dose 60 minutes before treatment. Experimental group 2: 28 patients will receive endodontic treatment and will receive the administration (orally) of a diclofenac potassium tablet 50mg in a single dose 60 minutes before treatment. CONDITION: C07.793.237 Pulpitis; Pain PRIMARY OUTCOME: To evaluate the effect of using preemptive oral medication with dexamethasone or diclofenac potassium on the success of inferior alveolar nerve block 15 minutes after anesthesia and its influence on postoperative pain intensity 6, 12, 24, 48 and 72 hours after the end of the endodontic procedure. SECONDARY OUTCOME: Secondary outcomes are not expected. INCLUSION CRITERIA: Healthy patient (American Association of Anesthesiologists ‐ class I); having lower molar diagnosed with irreversible symptomatic pulpitis; aged between 20 and 45 years; both genders; endodontic treatment performed within the interval between 80 and 90 minutes performed in patients who did not take any type of analgesic medication in the 12 hours preceding the endodontic treatment
Epistemonikos ID: b933a91cfec00c2dcbf7b1eaa0a148959441ce3c
First added on: Feb 20, 2024