A Randomized Controlled Trial of Individualized a-tACS in Patients with Disorders of Consciousness

INTERVENTION: Control group:Sham stimulation;Experimental group:Transcranial electrical stimulation; CONDITION: Confusion of consciousness PRIMARY OUTCOME: Revised Coma Recovery Scale; SECONDARY OUTCOME: Revised Coma Recovery Scale;Revised Coma Recovery Scale;Electroencephalogram; INCLUSION CRITERIA: 1. Age range: 18 ‐ 75 years old; 2. At least 28 days after acquired brain injury; 3. The CRS‐R screening was conducted by a trained qualified assessor, and the diagnosis was Doc; 4. Stable vital signs and clinical condition; 5. In the resting state EEG, stable alpha peaks of 7 ‐ 13 Hz were detected by at least two adjacent electrodes at the posterior part, with the peak value higher than the non‐periodic background and the frequency difference between the two being = 0.5 Hz; 6. The doses of main arousal, sedation and anti‐epileptic drugs were stable at least 3 ‐ 5 days before the baseline; 7. The legal representative understood the study and signed the informed consent.