Study to Assess Adverse Events and How Effective NOA LIFT is Compared to JUVÉDERM VOLIFT With Lidocaine for the Correction of Nasolabial Folds in Adults

Nasolabial folds (NLFs) are wrinkles that run from the sides of the nose to the cornersof the mouth. The goal of this study is to evaluate how safe and effective NOA LIFT iscompared to JUVÉDERM VOLIFT with Lidocaine for correcting moderate to severe nasolabialfolds in adults.NOA LIFT and JUVÉDERM VOLIFT with Lidocaine are hyaluronic acid‐based dermal fillersbeing evaluated for the treatment of nasolabial folds. Participants are randomly placedinto 1 of 2 treatment groups. There is a 2 in 3 chance that participants will be assignedto the NOA LIFT group and a 1 in 3 chance of being assigned to the VOLIFT group. Around288 adult participants with moderate to severe nasolabial folds will be enrolled atmultiple sites in China.Participants will receive deep dermis injections of either NOA LIFT or JUVÉDERM VOLIFT.The study duration is approximately 12 months after the initial treatment.There may be higher treatment burden for participants in this trial compared to theirstandard of care due to study procedures. Participants will attend regular visits duringthe study at a hospital or clinic. The effects of the treatment will be checked bymedical assessments, vital signs, laboratory tests, vision assessments, checking for sideeffects, and completing questionnaires.