Randomized Controlled Study to Evaluate the Clinical Outcomes of Rheumatoid Arthritis Treated with Method of Activating Blood Circulation by Removing Blood Stasis

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2010
INTERVENTION: Group A:observation group: Leflunomide Tablets, from the first day to the third day, 50mg, qd, po, then 20mg, qd, po. Ligustrazine Powder‐Needle, 0.12g, solubling in 5% GS/NS 100ml, qd, iv, in 30 to 60 minutes. ;Group B:control group: Leflunomide Tablets, from the first day to the third day, 50mg, qd, po, then 20mg, qd, po. ; CONDITION: M06.991 Rheumatoid Arthritis PRIMARY OUTCOME: Rest pain, pressing pain on joints, arthrocele, early morning stiffness, average grip of both hands; SECONDARY OUTCOME: Laboratory examinations: ESR, RF, CRP, IgA, IgG, IgM, hemorheology, X‐ray, Pattern information of Chinese Medicine; INCLUSION CRITERIA: 1. Be diagnosed with RA as defined by the 1987 America College of Rheumatology (ACR) criteria, and the disease progression is in the I, II, or III phase, in active phase; 2. Sign the informed consent by patient or guardian; 3. Platelet count>=100*10^9/L.
Epistemonikos ID: b7eef484778286cb40e4f4c0b6a474c7c79f5686
First added on: Mar 24, 2022