Treatment of community acquired alveolar pneumonia in 6-59 month old children: comparing amoxicillin (80 mg/kg) for 10 days with short course of amoxicillin (80 mg/kg) for 3 days

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2005
INTERVENTION: Randomised controlled trial comparing amoxicillin (80 mg/kg) for 10 days with a short course of amoxicillin (80 mg/kg) for 3 days. CONDITION: Community acquired alveolar pneumonia. ; Respiratory ; Pneumonia PRIMARY OUTCOME: The primary outcome is treatment failure defined as:; 1. Any patient who will need the study drug replaced; 2. Admission to the pediatric wards due to deterioration in medical condition, both after the first 24 hours following the initiation of treatment SECONDARY OUTCOME: No secondary outcome measures INCLUSION CRITERIA: Participation in the study will be all infants and young children who meet the following criteria: 1. Children aged 6‐59 months who are residents of the Negev region of southern Israel attending the Soroka emergency room (ER) 2. Provision of informed consent required for follow‐up visits (visits 2 and 3) 3. Body temperature measured as 38 °C or higher 4. White blood cells count (WBC): 15,000 cells/ml or higher 5. Chest X‐ray with alveolar pneumonia as defined by World Health Organisation (WHO)
Epistemonikos ID: b7ec3e2ad4eaf367ac7392c72a0adba36f37710b
First added on: Aug 21, 2024