Intellectual development at age 12 years of children with congenital hypothyroidism diagnosed by neonatal screening.

Authors Glorieux J, Dussault J, Van Vliet G -More
Category Primary study
JournalThe Journal of pediatrics
Year 1992
Links Pubmed
Twenty-seven patients with congenital hypothyroidism diagnosed by neonatal screening were examined at the age of 12 years. The 12 patients with severe hypothyroidism at diagnosis (thyroxine < 2 micrograms/dl (< 26 nmol/L), and area-of-the-knee epiphyses < 0.05 cm2 had a lower IQ than the 15 patients with less severe hypothyroidism (mean +/- SD, 89 +/- 17 vs 104 +/- 10; p < 0.007). Comparisons of patients and siblings confirm that this difference was due to the severity of hypothyroidism.
Epistemonikos ID: b6019e51270f5947d5ed1e70c054a89aabda697a
First added on: Apr 17, 2015