Garlic promotes an acute reduction in blood pressure but does not increase the effect of exercise in promoting a reduction in blood pressure

INTERVENTION: 57177 Participants performed four experimental sessions randomly determined for each subject: two aerobic exercise sessions, one with prior garlic intake (AGE) and another with placebo (PL) and two other non‐exercise procedures, with AGE intake and no AGE (Control) at the same time were ingested in the exercise sessions. The procedures were performed with an interval of at least 48 hours. BP were recorded at rest and every ten minutes during a recovery period of 60 minutes after exercise or in an equivalent period in non‐exercise procedures. Blood samples were taken at rest and immediately after exercise, or at an equivalent time in both protocols without exercise, for later analysis of the serum concentration of malondialdehyde (MDA) and nitrite. Capsules were made with the dosage of 750 mg of AGE, which were used in this way to minimize odor and characteristic strong flavor of garlic. Placebo was also given in capsules of the same color and shape containing 750 mg of pharmaceutical talc. Participants ingested an AGE or placebo capsule 30 minutes before the start of the experimental sessions and remained at rest until the beginning of the experimental protocols. The literature has shown supplementation with garlic in most studies between 500mg and 2400mg daily, but there are also high doses above this range as well as low doses below this range. We then decided to use a 750mg dose as it can be considered an intermediate dose, close to the lower values, as a safety measure (Shabani et al. 2018). Fifteen volunteers participated in the four groups in a cross‐over model. CONDITION: 5639 Garlic; Post‐Exercise Hypotension; Arterial Hypertension; Aerobic Exercise PRIMARY OUTCOME: Evaluate post‐exercise hypotension in hypertensive individuals after supplementation with aged garlic extract. It is expected to find the pressure reduction after garlic supplementation, as well as the potentiation of hypotension caused by the physical exercise session. It will be checked by the method of measuring blood pressure, using a sphygmomanometer. The behavior of post‐supplementation and post‐exercise blood pressure was observed and compared to baseline values to detect post‐exercise hypotension and its magnitude. From the verification of a statistically significant variation (p<0.05), we will have the indication that the supplementation was effective to reduce blood pressure and potentiate the hypotensive effect of exercise SECONDARY OUTCOME: Secondary outcomes are not expected INCLUSION CRITERIA: Have at least 3 months of physical exercise; should be hypertensive