Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2026
The goal of this clinical trial is to determine whether continuous nefopam administration, as part of a multimodal analgesia strategy, reduces opioid consumption and improves patient satisfaction after pancreatoduodenectomy. The main questions are: Does nefopam administration reduce opioid consumption after pancreatoduodenectomy? Does nefopam administration reduce postoperative pain levels after pancreatoduodenectomy? Researchers will compare two other analgesic strategies, namely continuous lidocaine infusion and epidural analgesia, to assess whether they lead to better outcomes. Participants will complete the QoR-15 questionnaire and report their pain levels at predefined time points before and after surgery.
Epistemonikos ID: b4e4a0629d22feb336d898b676f78acc1f5280af
First added on: Feb 21, 2026