FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2009
FOLFOX\* followed by FOLFIRI\*\* or reverse sequence treatment regimen have been used as a standard treatment modality in metastatic colorectal cancer.Oxaliplatin and Irinotecan were used for advanced gastric cancer also. The investigators study was designed to evaluate the safety and efficacy of FOLFOX followed by FOLFIRI or reverse sequence treatment regimen as a first-line and second line therapy for patients with relapsed or metastatic gastric cancer similar with colorectal cancer. \*FOLFOX: oxaliplatin followed by leucovorin before bolus 5-FU followed by continuous infusion 5-FU \*\*FOLFIRI: irinotecan followed by leucovorin before bolus 5-FU followed by continuous infusion 5-FU
Epistemonikos ID: b47fa40a8e6bc97c189862a01dabd1246654b1bd
First added on: May 05, 2024