Effect of Atorvastatin and CoQ10 on stroke

INTERVENTION: Atorvastatin = 40 mg/day.oral, Coadministration with CoQ10= 300 mg/day Three times a day. 30 days. oral. Atorvastatin= 40 mg/day,daily 30 days, oral Intervention 1: Atorvastatin = 40 mg/day.oral, Coadministration with CoQ10= 300 mg/day Three times a day. 30 days. oral. Intervention 2: Atorvastatin= 40 mg/day,daily 30 days, oral. Treatment ‐ Drugs CONDITION: Cerebral infarction ischemic stroke. ; Cerebral infarction PRIMARY OUTCOME: Cognitive performance. Timepoint: admission‐ 72 houre‐after 30 day. Method of measurement: Mini‐Mental State Examination(MMSE). Degree of disability. Timepoint: Admission‐ After 30 day. Method of measurement: Modified Rankin Scale (MRS). Glial fibrillary acidic protein(GFAP). Timepoint: admission‐ 72 houre‐after 30 day. Method of measurement: eliza kit. Motor function and verbal. Timepoint: admission‐ 72 houre‐after 30 day. Method of measurement: National Institutes of Health Stroke Scale(NIHSS). INCLUSION CRITERIA: INCLUSION CRITERIA: (patients with ischemic stroke involving the middle cerebral artery, confirmed by computed tomography scanning and clinical symptoms; range of age 50‐70 years; not to receive statins continuously before entering the study; not to receive antioxidants (such as vitamin C and E) constantly; not to receive anti‐inflammatory drugs (steroids, nonsteroidal anti‐inflammatory) constantly; not affected by AIDS and neurodegenerative diseases (e.g. Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, multiple sclerosis); no loss of consciousness level due to any reason except stroke (such as shock, alcohol consumption or intoxication); non‐pregnancy; non‐epilepsy; patient`s consent).Exclusion criteria: (patient's death during the study; lack of patient`s availability to follow‐up; no tendency to attend in next follow‐up).