Evaluation of the effect of Colchicine in the patients with Acute Coroanry Syndrome

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Intervention Group: This group will receive standard treatment of ACS plus 0.5 mg per day Colchicine for 6 months. Intervention 2: Control Group: This group will receive standard treatment of ACS plus Placebo for 6 months. CONDITION: Acute Coronary Syndrome. ; ST elevation (STEMI) and non‐ST elevation (NSTEMI) myocardial infarction PRIMARY OUTCOME: All Cause Mortality. Timepoint: We will follow up all patients 7 days after discharge from the hospital and then monthly to assess mortality by telephone. They will also be visited every two months. Method of measurement: Questioning the patient and the patient,s visitor; and reviewing the patient's documents. Decompensated Heart Failure. Timepoint: We will follow up all patients 7 days after discharge from the hospital and then monthly to assess Decompensated Heart Failure by telephone. They will also be visited every two months. Method of measurement: Questioning the patient and the patient,s visitor; and reviewing the patient's documents. Hospitalization due to typical chest pain (Acute Coronary Syndrome). Timepoint: We will follow up all patients 7 days after discharge from the hospital and then monthly to assess Hospitalization due to typical chest pain (Acute Coronary Syndrome) by telephone. They will also be visited every two months. Method of measurement: Questioning the patient and the patient,s visitor; and reviewing the patient's documents. Stroke. Timepoint: We will follow up all patients 7 days after discharge from the hospital and then monthly to assess Stroke by telephone. They will also be visited every two months. Method of measurement: Questioning the patient and the patient,s visitor; and reviewing the patient's documents. INCLUSION CRITERIA: Patients who have completed the informed consent form Patients aged 40‐70 years with history of chest pain who have undergone Coronary Angiography with the aim of medical treatment or who have undergone Total or Near Total Revascularization Whose information and follow ups are completed
Epistemonikos ID: b3291f10c8f9ab500990a782d83b3780d8963b25
First added on: Jul 22, 2023