A randomized, double-blind, placebo-controlled, parallel-group, single-center clinical trial to study the effect of Bifidobacterium longum BB536 ingestion on anemia improvement

INTERVENTION: Daily ingestion of 2 capsules containing Bifidobacterium longum BB536 for 12 weeks. Daily ingestion of 2 placebo capsules devoid of Bifidobacterium longum BB536 for 12 weeks. CONDITION: Anemia PRIMARY OUTCOME: hemoglobin, red blood cell, serum ferritin SECONDARY OUTCOME: hematocrit, serum transferrin, total iron binding capacity (TIBC), reticular red count, total serum iron, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), transferrin‐saturation, defecation frequency, fecal property INCLUSION CRITERIA: (1) Adult women who are 20 to 65 years old at the time of agreement acquisition (2) Subjects whose Hb levels were less than 13 g/dL by a medical examination of 2014.