A Study on the Efficacy and Safety of Entacapone in the Treatment of Pain in Parkinson’s Disease

INTERVENTION: intervention group:Treatment with Entacapone;control group:Standard treatment for Parkinson’s disease; CONDITION: Patients clinically diagnosed with Parkinson’s pain, with a pain score of =4 on the Numerical Rating Scale (NRS) PRIMARY OUTCOME: Mumeric rating scales score; SECONDARY OUTCOME: Self‐Rating Anxiety Scale? Self‐rating depression scale;Pittsburgh sleep quality index, PSQI;Brief Pain Inventory,BPI; INCLUSION CRITERIA: 1. Participants must have given their voluntary consent and signed the informed consent form for this trial; 2. Aged 18–80 years, regardless of gender; 3. Patients with a clinical diagnosis of Parkinson's disease‐related pain, with a pain score of >=4 on the Numerical Rating Scale (NRS); 4. Patients with a Hohen & Yahr (H‐Y) stage of <=IV; 5. Have not participated in any clinical trials within the three months prior to the trial.