Three-armed study for therapy of primary and secondary syphilis in HIV infection

INTERVENTION: Intervention 1: ceftriaxone 1g i.v. for 10 days Intervention 2: Bezathine penicillin 2x1,2 Mio i.E. i.m. once Intervention 3: benzathine penicillin 2x 1,2 Mio i.E. i.m. day 1, 8, 15 CONDITION: A53.9 ‐ Syphilis, unspecified PRIMARY OUTCOME: treatment failure defined as:; ‐retreatment or; ‐treatment with any antibiotic active against treponema pallidum or; ‐no reduction by 2 titer levels in VDRL or FTAabs19S IgM after 48 weeks INCLUSION CRITERIA: ‐HIV positive Patients with serologically proven early syphilis