Comparing Air And Lidocaine For Inflating The Breathing Tube Cuff And Their Effects On Blood Pressure And Heart Rate When The Tube Is Removed After The Surgery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Alkalinized 2 Percent Lignocaine In Endotracheal Tube Cuff: Endotracheal Tube Cuff Inflated After Intubation With Alkalinized 2 Percent Lignocaine 10mL Prepared Using 9mL 2 Percent Lignocaine And 1mL 8.4 Percent Sodium Bicarbonate And Inflated Till Audible Leak Is Heard On Hemodynamic Responses 5 Minutes Before Extubation At Extubation 5 Minutes 10 Minutes 15 Minutes And 30 Minutes After Extubation Control Intervention1: Air In Endotracheal Tube Cuff: Endotracheal Tube Cuff Inflated With Air After intubation and inflated Till Audible Leak Is Heard On Hemodynamic Responses 5 Minutes Before Extubation At 5 minutes 10 Minutes 15 Minutes 30 Minutes After Extubation CONDITION: Health Condition 1: K801‐ Calculus of gallbladder with othercholecystitis Health Condition 2: K36‐ Other appendicitis Health Condition 3: K469‐ Unspecified abdominal hernia without obstruction or gangrene PRIMARY OUTCOME: To Compare Hemodynamic Responses Heart Rate Systolic Blood Pressure Diastolic Blood Pressure During Extubation Among Two Study GroupsTimepoint: 5 Minutes Before Extubation At Extubation 5 Minutes 10 Minutes 15 Minutes 30 Minutes After Extubation SECONDARY OUTCOME: To Compare Hemodynamic Responses Heart Rate Systolic Blood Pressure Diastolic Blood Pressure After Extubation Among Two Study GroupsTimepoint: 10 Minutes 15 Minutes 30 Minutes To Compare The Incidence Of Cough Sore Throat Hoarseness Of Voice At 24 Hours After Extubation Among Two Study GroupsTimepoint: 24 Hours INCLUSION CRITERIA: 1 Patient Who Have Given Informed And Written Consent 2 American Society Of Anaesthesiologists Physical Status Classification 1 And 2 3 Elective Surgeries Requiring General Anaesthesia
Epistemonikos ID: b10bfc0e3d85a3955ae4f70fab0959aa0c60428d
First added on: Oct 08, 2026