Effects of a workout program in patients with HIV and cocktail use for over than one year and treated at a university hospital: a randomized clinical trial

Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2015
INTERVENTION: C02.782.815.616.400 E02.779.483.875 Experimental group: 17 people infected with HIV and receiving HAART will perform twelve weeks of periodized resistance training (36 sessions), three times a week in an appropriate place to practice exercises. The total duration of each session is approximately one hour.The exercises will be supervised by a trained and qualified professional to guide the exercise. Control group:. 17 people infected with HIV and receiving HAART will receive orientation to keep daily habits. CONDITION: B20‐B24 Human immunodeficiency virus (HIV), Acquired Immunodeficiency Syndrome (AIDS) ; B20‐B24 PRIMARY OUTCOME: Reduction of proinflammatory cytokines concentrations of IL‐1beta, IL‐6 and TNF‐alpha and increased anti‐inflammatory cytokine IL‐10. SECONDARY OUTCOME: Increase in the number of CD4 + and CD8 + peripheral blood, reduction of viral load; fasting glucose; LDLc, triglycerides and total cholesterol. Increase of HDL‐c; number of lymphocytes in the peripheral blood; muscle strength; and improved quality of life. INCLUSION CRITERIA: Be patient infected with HIV and use of antiretrovital therapy for over one year seen at the Infectious and Parasitic Diseases sector of a university hospital. Be older than 18 and less than 60. Having health conditions for the practice of the proposed exercise. Being sedentary. Having availability displacement three times per week for the training local. Target sample: 34 patient.
Epistemonikos ID: b0c5bb44e2dd08159d43c2c8c0e4f10306b504e2
First added on: Aug 23, 2024