Randomised placebo controlled trial on the safety and efficacy of BSP-201 in osteoarthritis

INTERVENTION: 2250mg/day Sheabutter extract (BSP‐201) capsules over a 15 week period CONDITION: Osteoarthritis of the knees and/or hips PRIMARY OUTCOME: Change in Western Ontario and McMaster Universities (WOMAC) score from baseline SECONDARY OUTCOME: Change in Comprehensive Osteoarthritis Test (COAT) score. Change in Quality of Life (Short Form 36). Change osteoarthritis biomarkers including markers for fibrinolysis, coagulation, inflammation, cartilage synthesis and degredation and bone formation and resortion. Paracetamol Usage. INCLUSION CRITERIA: X‐ray and clinical evidence of osteoarthritis of the knees and/or hipsTotal WOMAC score of 30 or more at baseline.Good general health.Adequate venous access.