The Difference in the Mechanism of Action Between Two Brands of Dexamfetamine in Adults With ADHD

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2023
The goal of this clinical trial is to compare in the pk/pd profiles of magisterial dexamfetamine and Tentin in adults with Attention Deficit Hyperactivity Disorder (ADHD). The main question\[s\] it aims to answer are: Q1: is there a difference between pk/pd profiles of the two forms of dexamfetamine? Q2: how does the pharmacokinetic variability influences the objective and subjective (side) effects experienced by adult patients with ADHD? Participants will: * take the Quantified behavior Test for analysis of objective effects. * undergo blood sampling for analysis of the plasma concentration of dexamphetamine. * undergo blood pressure and heart rate measurements. * fill out 4 types of questionnaires. Researchers will compare the outcomes between magisterial dexamphetamine and Tentin use in a crossover setting.
Epistemonikos ID: aeba535603a6a09c38b70df5cf9e2cf78bc7ae4e
First added on: May 14, 2024