Comparison of the Effects of Fospropofol Disodium versus Propofol on Postoperative Delirium in Elderly Patients Undergoing Radical Colorectal Cancer Surgery: a Randomized Controlled Trial

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Fospropofol disodium group:Anesthesia was induced and maintained using fospropofol disodium;Propofol group:Anesthesia was induced and maintained using propofol; CONDITION: Postoperative Delirium in Elderly Patients with Colorectal Cancer PRIMARY OUTCOME: The incidence of postoperative delirium (POD); SECONDARY OUTCOME: Postoperative recovery quality;Heart rate and blood pressure at various intraoperative time points;The area under the curve (AUC) for hypotension (MAP <65 mmHg or a decrease >20% from baseline);Total dosage of vasoactive agents; INCLUSION CRITERIA: 1.Aged >=65 years, regardless of gender. 2.American Society of Anesthesiologists (ASA) physical status classification II‐III. 3.Scheduled to undergo elective radical colorectal cancer surgery under general anesthesia. 4.Provision of written informed consent by the patient or their legal guardian.
Epistemonikos ID: ac8c87071d87ef96af171aabf4dd5a0b4b13c8b3
First added on: Oct 08, 2026