[Therapeutic effect of tianma gouteng yin in the treatment of asthenic yin causing predominant yang in elderly hypertensive patients and its influence on quality of life]

OBJECTIVE: To observe the clinical curative effect of modified Tianma Gouteng decoction, a traditional Chinese medicine decoction, in the treatment of elderly hypertensive patients with syndrome of yin deficiency and yang hyperactivity and its influence on quality of life. METHODS: A total of 80 elderly hypertensive patients admitted to the hospital from August 2016 to February 2017 were selected and divided into observation group and control group with 40 cases in each group according to the random number table method. The control group was treated with nifedipine controlled-release tablets, and the observation group was additionally treated with modified Tianma Gouteng Decoction. After 8 weeks of treatment, the antihypertensive clinical curative effect and traditional Chinese medicine symptom curative effect were compared between the two groups, and the quality of life of the patients in the two groups was evaluated by using the short health survey form. RESULTS: After 8 weeks of treatment, the total effective rate of blood pressure reduction in the observation group was 87.00% higher than that in the control group (70.00%), and the difference was statistically significant (P<0.05). After 8 weeks of treatment, the total effective rate of improving TCM symptoms in the observation group was 92.50%, which was higher than that in the control group (77.00%), and the difference was statistically significant (P<0.05). After treatment, SBP and DBP in both groups decreased compared with those before treatment, and the differences were statistically significant (P<0.05). After treatment, there was no significant difference in the levels of SBP and DBP between the two groups (P>0.05). After treatment, the scores of each dimension of the SF-36 scale (physiological function, physical function, physical pain, vitality, social function, emotional function, mental health, and overall health) in the two groups were higher than those before treatment, and the physical The scores of pain, mental health and general health were higher than those of the control group, and the difference was statistically significant (P<0.05). During the medication period, blood, urine and stool routines, liver and kidney functions were within the normal range in the two groups. In the treatment group, there was 1 case of stomach discomfort and 1 case of diarrhea, which were changed to Chinese medicine after meals, and then the symptoms were relieved; in the observation group, 2 cases had transient mild ankle edema, and the symptoms disappeared spontaneously without special treatment. The incidence of adverse reactions in both groups was 5.00%, and there was no significant difference between the two groups (P>0.05). CONCLUSION: Modified Tianma Gouteng decoction has good clinical curative effect in treating elderly hypertensive patients with syndrome of yin deficiency and yang hyperactivity, and has advantages in improving TCM symptoms, body pain, mental health and overall health, and can improve the quality of life of patients.