Serenoa repens, cucurbita pepo, lycopene and selenium as an adjunct to the treatment of chronic bacterial prostatitis with antibiotics

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2017
INTERVENTION: Participants are randomised into two groups (block randomisation, computer generated algorithm). Both groups receive antibiotic treatment for 15 days as a part of their regular treatment of chronic bacterial prostatitis. One group will receive 6 months of treatment with one capsule per day of the product (Serenoa Repens, Cucurbita Pepo, Lycopene & Selenium), while the other group will receive one capsule per day for the same time period containing corn oil (placebo). The study will compare the groups' scores in the two basic questionnaires National Institute of Healths' Chronic Prostatitis Symptom Index (NIH‐CPSI) and International Prostate Symptom Score (IPSS), as well as changes in the clinical measurements Qmax, residual volume and prostate volume observed 1, 3, 6 and 12 months after the initial visit. CONDITION: Chronic bacterial prostatitis and lower urinary tract symptom (LUTS) ; Urological and Genital Diseases ; Chronic prostatitis PRIMARY OUTCOME: 1. Prostatitis symptoms assessed using the National Institute of Health's Chronic Prostatitis Symptom Index (NIH‐CPSI) and International Prostate Symptom Score (IPSS) at baseline, 1, 3, 6 and 12 months; 2. Qmax measured using specific uroflowmetry techniques at baseline, 3, 6 and 12 months; 3. Residual volume after urination and prostate volume measured by the urologist using ultrasound at baseline, 3, 6 and 12 months SECONDARY OUTCOME: Bacterial reinfection, assessed using Meares ‐ Stamey Test and microbiological testing at baseline, 3, 6 and 12 months INCLUSION CRITERIA: Adult patients with chronic bacterial prostatitis
Epistemonikos ID: ac07a7f62fa6fdc4b251c453ecfb6a1bbcc49a00
First added on: Aug 23, 2024