Effects of a Multidisciplinary Integrated Care Model on Care Outcomes in Patients With Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous clinicalsyndrome characterized by signs and symptoms of heart failure with a left ventricularejection fraction ≥50%. It disproportionately affects older adults and patients withmultiple comorbidities, including hypertension, diabetes, obesity, and chronic kidneydisease. Despite its high prevalence and disease burden, few pharmacologic therapies havedemonstrated consistent benefit in this population, highlighting the importance ofnon‐pharmacologic and system‐level interventions.This study investigates whether a Multidisciplinary Integrated Care Model (MICM) improvescare outcomes for patients with HFpEF compared with historical usual care. The MICMintervention integrates the following components: ‐ Cardiology‐led clinical management with guideline‐directed medical therapyoptimization ‐ Case management for care coordination, symptom monitoring, and care transitions ‐ Pharmacist‐led medication review and adherence support ‐ Nutritional counseling tailored to heart failure and comorbidity management ‐ Structured exercise and cardiac rehabilitation guidance ‐ Patient and caregiver education on self‐management and warning signsEligible participants are adults diagnosed with HFpEF (left ventricular ejection fraction≥50%) who receive care at the study institution. The intervention cohort will beprospectively enrolled and followed under the MICM program, while the historical controlcohort will consist of patients who received standard usual care prior to programimplementation, matched on relevant baseline characteristics.Outcomes of interest include heart failure‐related hospitalization and emergency visits,all‐cause mortality, functional capacity, NYHA functional class, and health‐relatedquality of life. Data will be collected through structured clinical assessments andmedical record review at baseline and at scheduled follow‐up intervals.Findings from this study are intended to generate evidence on the effectiveness ofmultidisciplinary, team‐based care models in improving outcomes for patients with HFpEF,and to inform future integrated care program development in similar clinical settings.