Outcomes of right lateral minithoracotomy versus conventional sternotomy in patients with mitral valve surgery: a randomized control trial

INTERVENTION: A:Mitral valve surgery via right lateral minithoracotomy;B:Mitral valve surgery via conventional sternotomy; CONDITION: Mitral valve disease PRIMARY OUTCOME: operation duration (min);CPB time (min);cross‐clamp time (min);ICU stay (days);ventilation time (hours);hospital stay (days);blood transfusion;drainage (ml);preoperative TTE;intraoperative TEE;postoperative TTE;CK;CK‐MB;cTnT;lung function;S100B;NSE;CRP;SIRS;VAS evaluation;Neuropsychological Tests;complications;death;3 month postoperative TTE;6 month postoperative TTE;12 month postoperative TTE;length of incision;quality of healing of incision;pain of incision;EQ‐5D;cost;minimum cost analysis; INCLUSION CRITERIA: 1) Patients with isolated mitral valve disease scheduled for mitral valve replacement or mitral valve annuloplasty in the condition that conservative treatment is invalid or indication for surgery is evident; 2) 18 to 75 years old. Male or female; 3) Mitral valve surgery via either right lateral minithoracotomy or conventional sternotomy is suitable; 4) Patients willing to sign the informed consent of this study.