Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2024
Metformin is the most prescribed blood sugar (glucose)-lowering medication for patients diagnosed with type 2 diabetes mellitus (T2DM). Metformin stimulates glucose uptake in skeletal muscle similar to the effects of exercise, though, some studies report that metformin may decrease exercise capacity. The main question this study looks to answer is: • Does metformin alter exercise capacity? Participants will: * Complete 5 exercise tests on a stationary bike. * Undergo a body composition test. * Take metformin and placebo. * Complete food and symptom logs. The researchers hypothesize that: • Metformin will reduce aerobic capacity.
Epistemonikos ID: aa9b49d773d773b90669a8257d4e3d9290e37630
First added on: Apr 17, 2025