A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's Ataxia

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This is a global, randomized, multi‐center, placebo‐controlled study to investigate theefficacy and safety of nomlabofusp in subjects with Friedreich's ataxiaThe main objectives of the study are to evaluate: ‐ The efficacy of subcutaneous (SC) administration of nomlabofusp compared to placeboat Week 72; 1) on the Upright Stability Score (USS) Subscale E of the ModifiedFriedreich's Ataxia Ratings Scale (mFARS), or 2) mFARS total score (Region specificobjective) ‐ The efficacy of SC administration of nomlabofusp compared to placebo at Week 72 onthe Clinical Global Impression of Severity (CGI‐S) score ‐ The safety and tolerability of SC administration of nomlabofusp
Epistemonikos ID: aa1afc9abdfb82f5d73581e82ade9a346a155c3b
First added on: Aug 21, 2026