Routine versus As-Needed Stress Testing in Asymptomatic Patients with High-Risk Coronary Calcium

INTERVENTION: Procedure/Surgery, Others(Routine stress testing ) : In this group, the preselected functional stress testing (exercise electrocardiography, stress echocardiography, nuclear imaging, or stress cardiac magnetic resonance imaging) will be performed within 3 months (± 2 months) according to the practice pattern of each participating center. CONDITION: Diseases of the circulatory system PRIMARY OUTCOME: Occurrence of major adverse cardiovascular events (a composite of death from cardiovascular causes, myocardial infarction, unplanned hospitalization leading to an urgent revascularization procedure, or heart failure hospitalization) SECONDARY OUTCOME: A. Death from cardiovascular causes B. Myocardial infarction C. Unplanned hospitalization leading to an urgent revascularization procedure D. Heart failure hospitalization E. Death from any causes F. A composite of death from cardiovascular cause or myocardial infarction G. Any hospitalization H. Performing revascularization procedure I. Performing invasive coronary angiography procedure J. Stroke K. Bleeding (Bleeding Academic Research Consortium type 2‐5) L. Total medical cost INCLUSION CRITERIA: 1. Subject must be at least 19 years of age. 2. Asymptomatic patients with high‐risk coronary calcium (Agatston Score = 400) 3. Signed written informed consent