Safety and Immunogenicity Study of Na-GST-1 With or Without CpG

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2014
Na-GST-1 is a protein expressed during the adult stage of the hookworm life cycle that is thought to play a role in the parasite\'s degradation of host hemoglobin for use as an energy source. Vaccination with recombinant GST-1 has protected dogs and hamsters from infection in challenge studies. This study will evaluate the safety and immunogenicity of two formulations of Na-GST-1 in healthy adult volunteers when co-administered with the immunostimulant CpG 10104, a Toll-like Receptor-9 agonist.
Epistemonikos ID: a7d2fd77a729541fbe35d64a83440abb9e9b8ccf
First added on: May 11, 2024