Effect of time-restricted eating on gut microbiota and metabolism in hyperurecemic patients-a randomised clinical trial

INTERVENTION: Control group:Keep their daily dietary habits as usual;Interventional group:Time‐restricted eating; CONDITION: Hyperuricemia PRIMARY OUTCOME: Gut microbiota after 4‐week of time‐restricted eating; SECONDARY OUTCOME: Blood glucose after 4‐week of time‐restricted eating;Serum uric acid after 4‐week of time‐restricted eating;Blood lipids after 4‐week of time‐restricted eating; INCLUSION CRITERIA: 1.Voluntarily sign the informed consent form; 2.Aged between 18 and 35 years; 3.Meet the diagnostic criteria for hyperuricemia as defined in the 2019 Chinese Guidelines for the Diagnosis and Management of Hyperuricemia and Gout: fasting serum uric acid levels greater than 420 µmol/L on two separate occasions; 4.Gender: both male and female are eligible; 5.Able to adhere to the study or follow‐up procedures;