Comparing efficacy of music therapy, sucrose and combination of the two for pain relief in neonates undergoing heel prick procedure.

INTERVENTION: Study neonate undergoing heel prick procedure for blood collection will get in random order ‐ Oral sucrose (Sterile 24%), Music therapy and combination of the above two methods in addition to standrad practice of swaddling and oral pacifier. Intervention I (MT) ‐ Music therapy Intervention II (S) ‐ Oral sucrose (24 %) with no music Intervention III (MT+S) ‐ Oral sucrose (24 %) with music therapy MT group ‐ In MT group the neonate will be exposed to Passive music therapy with instrumental lullabies with sounds up to 65 dB starting 20 minutes before the heel prick, continuing for 6 minutes after the painful procedure. S group – In S group the neonates will have no music. He/she will have oral sucrose (24 % sterile solution) 0.5 ml, two minutes prior to the beginning of the heel prick as per the current hospital protocol. MT+S group ‐ In MT+S group the neonate will be exposed to Passive music therapy with instrumental lullabies with sounds up to 65 dB starting 20 minutes before the heel prick, continuing for 6 minutes after the painful procedure. In addition he/she will then have oral sucrose (24 % sterile solution) 0.5 ml, two minutes prior to the beginning of the heel prick as per the current hospital protocol. This is a crossover study with each neonate getting all three interventions in random order. There will be a minimum of 40 minutes of 'wash‐out' period between subsequent interventions. CONDITION: Neonatal Pain PRIMARY OUTCOME: Is Music therapy or combination of music therapy with sucrose better for pain relief during heel prick procedure when compared with oral sucrose using PIPP score for neonates. SECONDARY OUTCOME: Is the heart rate more stable in neonates exposed to music therapy as compared to sucrose 24 %. The heart rate will be assessed by continuous video recording of the pulse oximeter, connected to the newborn with saturation probe. Is the oxygen saturation more stable in neonates exposed to music therapy as compared to sucrose 24 %. The oxygen saturation will be assessed by continuous video recording of the pulse oximeter, connected to the newborn with saturation probe. INCLUSION CRITERIA: 1. Newborns >/= 32 weeks 2. Stable clinical condition with no need of CPAP/high flow/Ventilation 3. Anticipated need for repeated heel prick samples for monitoring and blood collection