Safety of Manuka honey CycloPower ophthalmic cream

INTERVENTION: Intervention involves external application of Manuka honey CycloPower ophthalmic cream (0.5‐1ml) to the skin of the upper and lower eyelids of one eye only (randomised to the right or left eye), once daily for 2 weeks. The fellow (untreated) eye serves as the control. Compliance is monitored through follow‐up telephone calls and the weighing of returned unused cream. CONDITION: Blepharitis PRIMARY OUTCOME: Skin hyperaemia as measured by VAS grading by the researcher ; SECONDARY OUTCOME: Dry eye signs as measured by keratography INCLUSION CRITERIA: 1. Male or female healthy subjects aged 18‐45 and in good health as determined by past medical history, physical examination, vital signs at screening. 2. Subjects must be able to communicate well with the investigator, to understand and comply with the requirements of the study and understand and sign the written informed consent. 3. Be willing not to wear contact lenses for 2 days prior to the start of the study and for the duration of the study