Homeopathy for Major Depressive Disorder

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2023
INTERVENTION: Homeopathy: Individualized homeopathic medication following the method of the sixth edition of the Organon Placebo: Indistinguishable solution containing 20 ml of 30% alcohol, administered in the same posology as the verum medication. CONDITION: Major Depressive Disorder PRIMARY OUTCOME: Score of the Beck‐II Depression Inventory (BDI‐II), self‐evaluated by the participant in weeks 0‐2‐4‐8‐12‐16‐20‐24‐28 and analyzed throughout the study in homeopathy and placebo partitions. SECONDARY OUTCOME: Evaluated in weeks 0‐2‐4‐8‐12‐16‐20‐24‐28: score of the Clinical Global Impression Scale; mental and physical health scores assessed by the 12‐Item Short‐Form Health Survey (SF‐12); participant's blinded preference for verum or placebo treatment at each block; clinically substantial worsening (characterized by an augmentation in BDI inclusion score greater than or equal to 30%), and Adverse Events. INCLUSION CRITERIA:
Epistemonikos ID: a62d2c771312fcb75bd3afea7304651cef804e11
First added on: Aug 26, 2024