Effect of Fasting on Insulin-induced Hypoglycemia Counterregulation in Healthy Humans

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2019
Iatrogenic hypoglycemia is still considered to be the number one barrier to effective glycemic control in patients with type 1 diabetes (T1D). In a previous study, we observed in dogs that liver glycogen content can be a determinant of hormonal and hepatic responses to insulin-induced hypoglycemia. In the experiments described herein, we will determine if nutritionally-manipulated changes in liver glycogen concentrations have an impact on hypoglycemic counterregulation in non-T1D control subjects.
Epistemonikos ID: a497daf9f494a3f8b33d81cacf4f8a7b59327b6f
First added on: May 07, 2024