Clinical trial of traditional Chinese medicine for chronic renal failure: an exploration for clinical pathway

INTERVENTION: Clinical trial group:Integrative medicating method including colon dialysis, San Qi oral liquid, NiaoDuQing granule and TCM formula with TCM differentiation, etc ;Retrospective group:Research on medical records ; CONDITION: Chronic renal failure ICD‐10:N18.807,N18.9 PRIMARY OUTCOME: Hospitalization expense;hospital day;time to the first initiation of dialysis; SECONDARY OUTCOME: TCM "zheng" score;serum urea;Hb;eGFR;Scr;indoxyl sulfate; INCLUSION CRITERIA: 1. Patients have chronic kidney disease with age from 18 to 80; 2. Patients who were in accordance with diagnosis standard of chronic renal failure both in western medicine and TCM; 3. Patients who haven't received peritoneal dialysis or hemodialysis with serum creatine level 133‐707umol/L, or creatine clearance rate level: 15‐60ml/min/1.73m2; 4. Patients who refuse to receive dialysis therapy with serum creatine level above 707umol/L.