Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This study compares two different root canal sealers, AH Plus and BioRoot Flow, to determine whether the type of sealer used during root canal treatment affects pain after treatment and oral health-related quality of life. Root canal treatment is performed to treat infection inside a tooth. Some patients may experience pain or discomfort after treatment, which can affect their daily activities and well-being. The study includes adults with asymptomatic apical periodontitis in a permanent tooth with one root and one root canal. Participants are randomly assigned to receive root canal treatment using either AH Plus, a resin-based sealer, or BioRoot Flow, a bioceramic-based sealer. All participants receive treatment in a single visit. Pain after treatment is assessed using a visual analog scale at 6 and 12 hours and on days 1, 2, 3, 5, 7, and 30. Oral health-related quality of life is assessed using the 14-item Oral Health Impact Profile (OHIP-14) questionnaire on day 7. The study also evaluates pain medication use and swelling after treatment. The findings may help clinicians better understand patients\' experiences following root canal treatment with these two sealers.
Epistemonikos ID: a42fd4dac3fb60fa28223d4df9150aea502ef6c9
First added on: Oct 22, 2026