A Study on Successful Maintenance for Atopic Dermatitis

INTERVENTION: Proactive therapy with topical agents alone Proactive therapy with topical agents plus an antihistamine (levocetirizine hydrochloride) at dose of 5mg once a day CONDITION: atopic dermatitis PRIMARY OUTCOME: The rate of the maintenance phase; of Atopic Dermatitis(time to recurrence of inflammation) INCLUSION CRITERIA: The first stage 1) Patients who are diagnosed as AD 2) Patients with more than moderate AD (according to severity scoring by JDA) who are needed daily treatment of steroids and tacrolimus. 3) Patients who are obtainable written informed consent. 4) Patients with more than 16 years old who are diagnosed as AD. ?Should be obtained written informed consent by the legally authorized representative If he or she is less than 20 years old. * moderate AD : according to severity scoring by Severity Score Index according to Standard guideline for management (authorized by Japanese Dermatological Association) The second stage 1) Subjects who were registered in 1st phase, and also had the inflammation symptom subside within 4 weeks during the course of standard therapy defined in the JDA guideline. 2) Subjects who had recurrence of inflammation symptom will be receive the standard therapy defined in the JDA guideline again. 3) Patients who are obta